August 1


Spironolactone Acne Treatment – How Does it Work?

By James

August 1, 2018

acne treatment, Spironolactone

Spironolactone is a drug used to treat high blood pressure. It is used in lowering high blood pressure, helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling caused by certain conditions like congestive heart failure, by removing excess fluid and improving symptoms such as breathing problems.

This medication is also used to treat low potassium levels and condition where the body is making too much of a natural chemical, aldosterone. Many women having acne, who have not seen positive results with over-the-counter acne drugs have experienced clearer skin with this medicine.

The US FDA has not approved Spironolactone for acne, but dermatologists all over the world are prescribing it off-label to women with severe hormonal acne breakouts.

spironolactone inhibits testosterone production and has anti-androgen properties. This means that it blocks the effect of some male hormones, like testosterone, from binding to receptors that can cause oil production in your glands, and women who have high hormone levels tend to see more breakouts on the lower face.

The use of Spironolactone, also known by its brand name Aldactone can be an effective way to stop that from happening.

How Does Spironolactone Acne Treatment Work?

Spironolactone acne treatment has an anti-androgen action that acts against the group of male hormones called androgens which are produced more in some women and believed to be the reason behind their acne breakouts.

Spironolactone blocks the androgen receptors and prevents the cells from absorbing these male hormones, helping to reduce hormonal fluctuations causing the acne.

Spironolactone acne treatment works only on women having hormonal acne, and studies conducted on this drug show that nearly 68% women with the tendency towards hormonal acne breakouts experienced improvement or complete clearing of their skin with Aldactone.

How to Use

Take this medication orally, as directed by a doctor, and if stomach upset occurs, take it with food or milk. It is best to take your dose early in the day, so as to prevent having to get up during the night to urinate. Dosage is based on your medical condition and response to therapy.

Take this medication regularly in order to get the most benefit from it, and remember to use it at the same time(s) each day as directed by an expert.

Do not increase your dose, take it more often than prescribed, or stop using this medicine without first consulting your doctor, and if your condition may become worse when the drug is suddenly stopped, ensure to inform your doctor.

Usage Directions for Aldactone

When taking Spironolactone acne treatment, dermatologists suggest that you start with 50 to 100mg daily dose. The lowest dose is usually prescribed first to see the results and gradually worked up over the course of next few days or weeks.

Doctors also take a complete medical history of the patient to determine appropriate dosage based on individual medical situations.

Patients must drink at least 8 to 10 glasses of water as Spironolactone is a diuretic, and if any side effects of Spironolactone acne treatment are noticed, it is important to notify the provider or your doctor.

Side Effects

Many people using this medication do not experience serious side effects.ButSpironolactone may lead to high levels of potassium, especially in patients with kidney problems, and if not treated, very high potassium levels can be fatal. Inform your doctor immediately if you notice slow/irregular heartbeat and muscle weakness.

Tell your doctor also if you experience fever, persistent sore throat, severe stomach/abdominal pain, persistent nausea/vomiting, vomit that looks like coffee grounds, dark urine, yellowing of the eyes/skin, easy bruising/bleeding.

Symptoms of a serious allergic reaction include rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, and troubled breathing.

Side Effects Include:

  • Dry mouth
  • Irregular menstrual cycle with spotting
  • Breast tenderness
  • Constant thirst
  • Dizziness
  • Headaches
  • Nausea and vomiting
  • Upset stomach, cramps or diarrhea
  • Increased potassium levels in the blood
  • Lower blood pressure


Before taking spironolactone, it is recommended that you tell your doctor or pharmacist if you have any other allergies. This Spironolactone may contain inactive ingredients, which can cause allergic reactions or other problems.

Ensure to talk to your pharmacist for more details before using this medication. Tell your doctor or pharmacist your medical history.

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